CIDRE

CIDRE: An illumination-correction method for optical microscopy

Uneven illumination affects every image acquired by a microscope. It is often overlooked, but it can introduce considerable bias to image measurements. The most reliable correction methods require special reference images, and retrospective alternatives do not fully model the correction process. Our approach overcomes these issues for most optical microscopy applications without the need for reference images.

The CIDRE software project is officially maintained on a GitHub repository at external pagehttps://github.com/smithk/cidre

DownloadDownload Matlab and Java Source code (with Fiji plugin) (ZIP, 8.2 MB)

If you use CIDRE in your research please refer to it via following reference:

K. Smith, Y. Li, F. Ficcinini, G. Csucs, A. Bevilacqua, and P. Horvath
external pageCIDRE: An Illumination Correction Method for Optical Microscopy, Nature Methods, Early Online Access 16 March 2015, doi:10.1038/NMETH.3323